Isolation and Properties of Porcine Thyrotropin-releasing Hormone

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Isolation and properties of porcine thyrotropin-releasing hormone.

Isolation on a preparative scale of thyrotropin-releasing rormone from porcine hypothalami is described. The yields ‘ram two batches of 100,000 and 165,000 hypothalami were !.8 mg and 4.4 mg, respectively. The material with thyro:ropin-releasing hormone activity, calculated to be purified Ibout 570,000 times, was active in mice at doses of 1 ng in jiuo, and stimulated the secretion of thyroid-s...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1969

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(17)36387-1